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Anti-p73 Antibody
Rabbit polyclonal antibody to p73
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | O15350 |
| Other Accession | Q9JJP2 |
| Reactivity | Human, Mouse, Rat, Monkey, Chicken, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 69623 Da |
| Gene ID | 7161 |
|---|---|
| Other Names | P73; Tumor protein p73; p53-like transcription factor; p53-related protein |
| Target/Specificity | Recognizes endogenous levels of p73 protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/50 - 1/200) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | TP73 |
|---|---|
| Synonyms | P73 |
| Function | Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. Is an activator of FOXJ1 expression (By similarity). It is an essential factor for the positive regulation of lung ciliated cell differentiation (PubMed:34077761). |
| Cellular Location | Nucleus. Cytoplasm. Note=Accumulates in the nucleus in response to DNA damage |
| Tissue Location | Expressed in striatal neurons of patients with Huntington disease (at protein level). Brain, kidney, placenta, colon, heart, liver, spleen, skeletal muscle, prostate, thymus and pancreas Highly expressed in fetal tissue. Expressed in the respiratory epithelium (PubMed:34077761). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human p73. The exact sequence is proprietary.
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