Anti-TOB (pS164) Antibody
Rabbit polyclonal antibody to TOB (pS164)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
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Primary Accession | P50616 |
Other Accession | Q61471 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 38155 Da |
Gene ID | 10140 |
---|---|
Other Names | TOB; TROB1; Protein Tob1; Transducer of erbB-2 1 |
Target/Specificity | Recognizes endogenous levels of TOB (pS164) protein. |
Dilution | WB~~WB (1/500 - 1/1000), IH (1/50 - 1/200) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | TOB1 |
---|---|
Synonyms | TOB, TROB1 |
Function | Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex (PubMed:23236473, PubMed:8632892). Mediates CPEB3-accelerated mRNA deadenylation by binding to CPEB3 and recruiting CNOT7 which leads to target mRNA deadenylation and decay (PubMed:21336257). |
Cellular Location | Cytoplasm. Nucleus. Note=Only a small fraction localizes to the cytoplasm except in late S- phase where more than half of proteins become cytoplasmic |
Tissue Location | Ubiquitous. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TOB (pS164). The exact sequence is proprietary.
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