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Anti-Beta-2 Adrenergic Receptor (pS355/S356) Antibody
Rabbit polyclonal antibody to Beta-2 Adrenergic Receptor (pS355/S356)
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Application 
| WB, IHC |
|---|---|
| Primary Accession | P07550 |
| Other Accession | P18762 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 46459 Da |
| Gene ID | 154 |
|---|---|
| Other Names | ADRB2R; B2AR; Beta-2 adrenergic receptor; Beta-2 adrenoreceptor; Beta-2 adrenoceptor |
| Target/Specificity | Recognizes endogenous levels of Beta-2 Adrenergic Receptor (pS355/S356) protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/50 - 1/200) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | ADRB2 |
|---|---|
| Synonyms | ADRB2R, B2AR |
| Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Early endosome. Golgi apparatus. Note=Colocalizes with VHL at the cell membrane (PubMed:19584355). Activated receptors are internalized into endosomes prior to their degradation in lysosomes (PubMed:20559325) Activated receptors are also detected within the Golgi apparatus (PubMed:27481942). |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Beta-2 Adrenergic Receptor (pS355/S356). The exact sequence is proprietary.
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