Anti-PAX6 Antibody
Rabbit polyclonal antibody to PAX6
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | P26367 |
Other Accession | P63015 |
Reactivity | Human, Mouse, Rat, Zebrafish, Chicken, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 46683 Da |
Gene ID | 5080 |
---|---|
Other Names | AN2; Paired box protein Pax-6; Aniridia type II protein; Oculorhombin |
Target/Specificity | Recognizes endogenous levels of PAX6 protein. |
Dilution | WB~~WB (1/500 - 1/1000) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | PAX6 |
---|---|
Synonyms | AN2 |
Function | Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Acts as a transcriptional repressor of NFATC1- mediated gene expression (By similarity). |
Cellular Location | Nucleus {ECO:0000250|UniProtKB:P63015}. [Isoform 5a]: Nucleus {ECO:0000250|UniProtKB:P63016} |
Tissue Location | [Isoform 1]: Expressed in lymphoblasts. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PAX6. The exact sequence is proprietary.
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