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Anti-PAX6 Antibody

Rabbit polyclonal antibody to PAX6

     
  • WB - Anti-PAX6 Antibody AP61127
    Western blot analysis of PAX6 expression in HEK293T (A) whole cell lysates.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P26367
Other Accession P63015
Reactivity Human, Mouse, Rat, Zebrafish, Chicken, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 46683 Da
Additional Information
Gene ID 5080
Other Names AN2; Paired box protein Pax-6; Aniridia type II protein; Oculorhombin
Target/Specificity Recognizes endogenous levels of PAX6 protein.
Dilution WB~~WB (1/500 - 1/1000)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name PAX6
Synonyms AN2
Function Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Acts as a transcriptional repressor of NFATC1- mediated gene expression (By similarity).
Cellular Location Nucleus {ECO:0000250|UniProtKB:P63015}. [Isoform 5a]: Nucleus {ECO:0000250|UniProtKB:P63016}
Tissue Location [Isoform 1]: Expressed in lymphoblasts.
Research Areas
Citations (0)
citation

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Background

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PAX6. The exact sequence is proprietary.

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$ 350.00
$ 175.00
Cat# AP61127
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