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Anti-p57 Kip2 (pT310) Antibody
Rabbit polyclonal antibody to p57 Kip2 (pT310)
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Application 
| WB, IF/IC, IHC |
|---|---|
| Primary Accession | P49918 |
| Other Accession | P49919 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 32177 Da |
| Gene ID | 1028 |
|---|---|
| Other Names | KIP2; Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57Kip2 |
| Target/Specificity | Recognizes endogenous levels of p57 Kip2 (pT310) protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/50 - 1/100), IF/IC (1/100 - 1/500) IF~~WB (1/500 - 1/1000), IH (1/50 - 1/100), IF/IC (1/100 - 1/500) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | CDKN1C |
|---|---|
| Synonyms | KIP2 |
| Function | Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life. |
| Cellular Location | Nucleus. |
| Tissue Location | Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human p57 Kip2. The exact sequence is proprietary.
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