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Anti-MLZE Antibody
Rabbit polyclonal antibody to MLZE
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9BYG8 |
| Other Accession | Q99NB5 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 57692 Da |
| Gene ID | 56169 |
|---|---|
| Other Names | MLZE; Gasdermin-C; Melanoma-derived leucine zipper-containing extranuclear factor |
| Target/Specificity | Recognizes endogenous levels of MLZE protein. |
| Dilution | WB~~WB (1/500 - 1/1000) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | GSDMC {ECO:0000303|PubMed:17350798, ECO:0000312|HGNC:HGNC:7151} |
|---|---|
| Function | [Gasdermin-C]: This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-C, N-terminal) binds to membranes and forms pores, triggering pyroptosis. |
| Cellular Location | [Gasdermin-C]: Cytoplasm, cytosol |
| Tissue Location | Expressed mainly in trachea and spleen (PubMed:11223543). In the esophagus, expressed in differentiating cells and probably in differentiated cells. Also detected in gastric epithelium (PubMed:19051310). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MLZE. The exact sequence is proprietary.
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