Anti-IRS1 (pS636) Antibody
Rabbit polyclonal antibody to IRS1 (pS636)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IF/IC, IHC |
---|---|
Primary Accession | P35568 |
Other Accession | P35569 |
Reactivity | Human, Mouse, Rat, Pig |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 131591 Da |
Gene ID | 3667 |
---|---|
Other Names | Insulin receptor substrate 1; IRS-1 |
Target/Specificity | Recognizes endogenous levels of IRS1 (pS636) protein. |
Dilution | WB~~WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500) IF~~WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | IRS1 |
---|---|
Function | May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity). |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IRS1 (pS636). The exact sequence is proprietary.
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