Anti-IDH3 beta Antibody
Rabbit polyclonal antibody to IDH3 beta
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | O43837 |
Reactivity | Human, Mouse, Rat, Monkey, Pig, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 42184 Da |
Gene ID | 3420 |
---|---|
Other Names | Isocitrate dehydrogenase [NAD] subunit beta mitochondrial; Isocitric dehydrogenase subunit beta; NAD(+)-specific ICDH subunit beta |
Target/Specificity | Recognizes endogenous levels of IDH3 beta protein. |
Dilution | WB~~WB (1/500 - 1/1000) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | IDH3B |
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Function | Plays a structural role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers. |
Cellular Location | Mitochondrion. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IDH3 beta. The exact sequence is proprietary.
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