Anti-Annexin A2 (pS26) Antibody
Rabbit polyclonal antibody to Annexin A2 (pS26)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IP |
---|---|
Primary Accession | P07355 |
Other Accession | P07356 |
Reactivity | Human, Mouse, Rat, Monkey, Bovine, SARS, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 38604 Da |
Gene ID | 302 |
---|---|
Other Names | ANX2; ANX2L4; CAL1H; LPC2D; Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; PAP-IV; Protein I; p36 |
Target/Specificity | Recognizes endogenous levels of Annexin A2 (pS26) protein. |
Dilution | WB~~WB (1/500 - 1/1000), IP (1/10 - 1/100) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | ANXA2 |
---|---|
Synonyms | ANX2, ANX2L4, CAL1H, LPC2D |
Function | Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:18799458, PubMed:22848640, PubMed:24808179). |
Cellular Location | Secreted, extracellular space, extracellular matrix, basement membrane. Melanosome. Note=In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Annexin A2 (pS26). The exact sequence is proprietary.
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