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Anti-Annexin A2 (pS26) Antibody

Rabbit polyclonal antibody to Annexin A2 (pS26)

     
  • WB - Anti-Annexin A2 (pS26) Antibody AP59966
    Western blot analysis of Annexin A2 (pS26) expression in mouse lung (A), rat lung (B), rat liver (C) whole cell lysates.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IP
Primary Accession P07355
Other Accession P07356
Reactivity Human, Mouse, Rat, Monkey, Bovine, SARS, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 38604 Da
Additional Information
Gene ID 302
Other Names ANX2; ANX2L4; CAL1H; LPC2D; Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; PAP-IV; Protein I; p36
Target/Specificity Recognizes endogenous levels of Annexin A2 (pS26) protein.
Dilution WB~~WB (1/500 - 1/1000), IP (1/10 - 1/100)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name ANXA2
Synonyms ANX2, ANX2L4, CAL1H, LPC2D
Function Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:18799458, PubMed:24808179, PubMed:22848640).
Cellular Location Secreted, extracellular space, extracellular matrix, basement membrane. Melanosome. Note=In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism
Research Areas
Citations (0)
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Background

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Annexin A2 (pS26). The exact sequence is proprietary.

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$ 350.00
$ 175.00
Cat# AP59966
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