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Anti-ALDOB Antibody
Rabbit polyclonal antibody to ALDOB
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | P05062 |
| Other Accession | Q91Y97 |
| Reactivity | Human, Mouse, Rat, Rabbit, Monkey, Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 39473 Da |
| Gene ID | 229 |
|---|---|
| Other Names | ALDB; Fructose-bisphosphate aldolase B; Liver-type aldolase |
| Target/Specificity | Recognizes endogenous levels of ALDOB protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/100 - 1/200) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | ALDOB {ECO:0000303|PubMed:15880727, ECO:0000312|HGNC:HGNC:417} |
|---|---|
| Function | Catalyzes the aldol cleavage of fructose 1,6-biphosphate to form two triosephosphates dihydroxyacetone phosphate and D- glyceraldehyde 3-phosphate in glycolysis as well as the reverse stereospecific aldol addition reaction in gluconeogenesis. In fructolysis, metabolizes fructose 1-phosphate derived from the phosphorylation of dietary fructose by fructokinase into dihydroxyacetone phosphate and D-glyceraldehyde (PubMed:10970798, PubMed:12205126, PubMed:20848650). Acts as an adapter independently of its enzymatic activity, exerts a tumor suppressor role by stabilizing the ternary complex with G6PD and TP53 to inhibit G6PD activity and keep oxidative pentose phosphate metabolism in check (PubMed:35122041). |
| Cellular Location | Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ALDOB. The exact sequence is proprietary.
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