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Anti-SENP7 Antibody
Rabbit polyclonal antibody to SENP7
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Application 
| WB |
|---|---|
| Primary Accession | Q9BQF6 |
| Other Accession | Q8BUH8 |
| Reactivity | Human, Mouse, Rat, Monkey, Pig, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 119658 Da |
| Gene ID | 57337 |
|---|---|
| Other Names | KIAA1707; SSP2; SUSP2; Sentrin-specific protease 7; SUMO-1-specific protease 2; Sentrin/SUMO-specific protease SENP7 |
| Target/Specificity | Recognizes endogenous levels of SENP7 protein. |
| Dilution | WB~~WB (1/500 - 1/1000) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | SENP7 {ECO:0000303|Ref.2, ECO:0000312|HGNC:HGNC:30402} |
|---|---|
| Function | Protease that acts as a positive regulator of the cGAS-STING pathway by catalyzing desumoylation of CGAS. Desumoylation of CGAS promotes DNA-binding activity of CGAS, subsequent oligomerization and activation (By similarity). Deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1 (PubMed:18799455). Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains (PubMed:18799455). Has very low efficiency in processing full-length SUMO proteins to their mature forms (PubMed:18799455). |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q8BUH8}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human SENP7. The exact sequence is proprietary.
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