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Anti-14-3-3 zeta (pS58) Antibody
Rabbit polyclonal antibody to 14-3-3 zeta (pS58)
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- BACKGROUND
Application 
| WB, IP, IF/IC, IHC |
|---|---|
| Primary Accession | P63104 |
| Other Accession | P63101 |
| Reactivity | Human, Mouse, Rat, Zebrafish, Pig, Chicken, Bovine, SARS |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 27745 Da |
| Gene ID | 7534 |
|---|---|
| Other Names | 14-3-3 protein zeta/delta; Protein kinase C inhibitor protein 1; KCIP-1 |
| Target/Specificity | Recognizes endogenous levels of 14-3-3 zeta (pS58) protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500), IP (1/10 - 1/100) IF~~WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500), IP (1/10 - 1/100) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | YWHAZ |
|---|---|
| Function | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways (PubMed:14578935, PubMed:15071501, PubMed:15644438, PubMed:16376338, PubMed:16959763, PubMed:31024343, PubMed:9360956). Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif (PubMed:35662396). Binding generally results in the modulation of the activity of the binding partner (PubMed:35662396). Promotes cytosolic retention and inactivation of TFEB transcription factor by binding to phosphorylated TFEB (PubMed:35662396). Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation (PubMed:16959763). In neurons, regulates spine maturation through the modulation of ARHGEF7 activity (By similarity). |
| Cellular Location | Cytoplasm. Melanosome. Note=Located to stage I to stage IV melanosomes. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human 14-3-3 zeta. The exact sequence is proprietary.
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