Anti-Beta-synuclein Antibody
Rabbit polyclonal antibody to Beta-synuclein
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IF/IC |
---|---|
Primary Accession | Q16143 |
Other Accession | Q91ZZ3 |
Reactivity | Human, Mouse, Rat, Monkey |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 14288 Da |
Gene ID | 6620 |
---|---|
Other Names | Beta-synuclein |
Target/Specificity | Recognizes endogenous levels of Beta-synuclein protein. |
Dilution | WB~~WB (1/500 - 1/1000), IF/IC (1/100 - 1/500) IF~~WB (1/500 - 1/1000), IF/IC (1/100 - 1/500) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | SNCB |
---|---|
Function | Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease. |
Cellular Location | Cytoplasm. |
Tissue Location | Expressed predominantly in brain; concentrated in presynaptic nerve terminals |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Beta-synuclein. The exact sequence is proprietary.
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