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Anti-Beta-2 Adrenergic Receptor (pS346) Antibody
Rabbit polyclonal antibody to Beta-2 Adrenergic Receptor (pS346)
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Application 
| WB |
|---|---|
| Primary Accession | P07550 |
| Other Accession | P18762 |
| Reactivity | Human, Mouse, Rat, Bovine, SARS, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 46459 Da |
| Gene ID | 154 |
|---|---|
| Other Names | ADRB2R; B2AR; Beta-2 adrenergic receptor; Beta-2 adrenoreceptor; Beta-2 adrenoceptor |
| Target/Specificity | Recognizes endogenous levels of Beta-2 Adrenergic Receptor (pS346) protein. |
| Dilution | WB~~WB (1/500 - 1/1000) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | ADRB2 |
|---|---|
| Synonyms | ADRB2R, B2AR |
| Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Early endosome. Golgi apparatus. Note=Colocalizes with VHL at the cell membrane (PubMed:19584355). Activated receptors are internalized into endosomes prior to their degradation in lysosomes (PubMed:20559325) Activated receptors are also detected within the Golgi apparatus (PubMed:27481942). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Beta-2 Adrenergic Receptor. The exact sequence is proprietary.
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