NSDHL Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IHC-F, IF, E |
---|---|
Primary Accession | Q15738 |
Reactivity | Rat, Pig, Dog, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 41900 Da |
Gene ID | 50814 |
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Other Names | Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating, 1.1.1.170, Protein H105e3, NSDHL, H105E3 |
Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | NSDHL |
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Synonyms | H105E3 |
Function | Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis (By similarity). Also plays a role in the regulation of the endocytic trafficking of EGFR (By similarity). |
Cellular Location | Endoplasmic reticulum membrane; Single-pass membrane protein. Lipid droplet {ECO:0000250|UniProtKB:Q9R1J0} Note=Trafficking through the Golgi is necessary for ER membrane localization. {ECO:0000250|UniProtKB:Q9R1J0} |
Tissue Location | Brain, heart, liver, lung, kidney, skin and placenta |
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