Rarres3 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IHC-F, IF, E |
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Primary Accession | Q9UL19 |
Reactivity | Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 18179 Da |
Gene ID | 5920 |
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Other Names | Phospholipase A and acyltransferase 4 {ECO:0000312|HGNC:HGNC:9869}, 2.3.1.-, 3.1.1.32, 3.1.1.4, HRAS-like suppressor 4, HRSL4, RAR-responsive protein TIG3, Retinoic acid receptor responder protein 3, Retinoid-inducible gene 1 protein, Tazarotene-induced gene 3 protein, PLAAT4 (HGNC:9869), RARRES3, RIG1, TIG3 |
Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | PLAAT4 (HGNC:9869) |
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Synonyms | RARRES3, RIG1, TIG3 |
Function | Exhibits both phospholipase A1/2 and acyltransferase activities (PubMed:19615464, PubMed:22605381, PubMed:22825852, PubMed:26503625). Shows phospholipase A1 (PLA1) and A2 (PLA2), catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids (PubMed:19615464, PubMed:22605381, PubMed:22825852). For most substrates, PLA1 activity is much higher than PLA2 activity (PubMed:19615464). Shows O- acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid (PubMed:19615464). Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N- acylphosphatidylethanolamine (NAPE), which serves as precursor for N- acylethanolamines (NAEs) (PubMed:19615464, PubMed:22605381, PubMed:22825852). Promotes keratinocyte differentiation via activation of TGM1 (PubMed:17762858). |
Cellular Location | Membrane; Single- pass membrane protein |
Tissue Location | Widely expressed. |
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