Histatin 1 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC-P, IHC-F, IF, ICC, E |
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Primary Accession | P15515 |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 6963 Da |
Gene ID | 3346 |
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Other Names | Histatin-1, Histidine-rich protein 1, Post-PB protein, PPB, His1-(31-57)-peptide, His1 31/57, His1-(12-38)-peptide, His1 12/38, Histatin-2, HTN1, HIS1 |
Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | HTN1 (HGNC:5283) |
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Synonyms | HIS1 |
Function | Histatins (Hsts) are cationic and histidine-rich secreted peptides mainly synthesized by saliva glands of humans and higher primates (PubMed:3286634, PubMed:3944083). Hsts are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). Hsts can be divided into two major groups according to their biological functions: antimicrobial Hsts (e.g. Hst 5/HTN3) and cell-activating Hsts (e.g. Hst 1/HTN1 and Hst 2/HTN1) (PubMed:32225006). Hst 1/HTN1 and Hst 2/HTN1 act in different cell types (epithelium, fibroblasts and endothelium) in oral and non-oral mucosa (PubMed:25903106, PubMed:28542418, PubMed:28751526, PubMed:32225006). |
Cellular Location | [Histatin-1]: Secreted. Mitochondrion. Endoplasmic reticulum membrane. Note=Hst 1 co-localized with mitochondria as well as the endoplasmic reticulum (ER) after internalization in host cells. |
Tissue Location | [Histatin-1]: Submandibular and parotid glands. |

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