ENOX1 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, IHC-F, IF, ICC, E |
---|---|
Primary Accession | Q8TC92 |
Reactivity | Rat, Pig, Dog, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 73348 Da |
Gene ID | 55068 |
---|---|
Other Names | Ecto-NOX disulfide-thiol exchanger 1, Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase, cCNOX, Cell proliferation-inducing gene 38 protein, Constitutive Ecto-NOX, cNOX, Hydroquinone [NADH] oxidase, 1.-.-.-, Protein disulfide-thiol oxidoreductase, 1.-.-.-, ENOX1 |
Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | ENOX1 |
---|---|
Function | Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 24 minutes and play a role in control of the ultradian cellular biological clock. |
Cellular Location | Cell membrane. Secreted, extracellular space Note=Extracellular and plasma membrane-associated |
Tissue Location | Expressed in lymphocyte cells, breast and breast cancer (at protein level). Found in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Found also in the serum of healthy volunteers or patients with disorders other than cancer. Probably shed into serum by cancer cells |
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