FLVCR Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC-P, IHC-F, IF, ICC, E |
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Primary Accession | Q9Y5Y0 |
Reactivity | Rat, Pig |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 59863 Da |
Gene ID | 28982 |
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Other Names | Feline leukemia virus subgroup C receptor-related protein 1, Feline leukemia virus subgroup C receptor, hFLVCR, FLVCR1, FLVCR |
Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | FLVCR1 {ECO:0000303|PubMed:16439531, ECO:0000312|HGNC:HGNC:24682} |
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Function | Uniporter that mediates the transport of extracellular choline and ethanolamine into cells, thereby playing a key role in phospholipid biosynthesis (PubMed:37100056, PubMed:38693265, PubMed:38778100). Choline and ethanolamine are the precursors of phosphatidylcholine and phosphatidylethanolamine, respectively, the two most abundant phospholipids (PubMed:38693265, PubMed:38778100). Transport is not coupled with proton transport and is exclusively driven by the choline (or ethanolamine) gradient across the plasma membrane (PubMed:38693265, PubMed:38778100). Also acts as a heme b transporter that mediates heme efflux from the cytoplasm to the extracellular compartment (PubMed:15369674, PubMed:20610401, PubMed:22483575, PubMed:23187127, PubMed:27923065). |
Cellular Location | [Isoform 1]: Cell membrane; Multi-pass membrane protein |
Tissue Location | Found all hematopoietic tissues including peripheral blood lymphocytes. Some expression is found in pancreas and kidney. |

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