Anti-MUC5AC Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC |
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Primary Accession | P98088 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Calculated MW | 585570 Da |
Gene ID | 4586 |
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Other Names | MUC5; Mucin-5AC; MUC-5AC; Gastric mucin; Lewis B blood group antigen; LeB; Major airway glycoprotein; Mucin-5 subtype AC tracheobronchial; Tracheobronchial mucin; TBM; Fragments |
Target/Specificity | Recognizes endogenous levels of MUC5AC protein. |
Format | Mouse IgG1. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | MUC5AC {ECO:0000303|PubMed:11535137, ECO:0000312|HGNC:HGNC:7515} |
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Function | Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system (PubMed:14535999, PubMed:14718370). Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD) (PubMed:14535999). |
Cellular Location | Secreted |
Tissue Location | Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Mouse monoclonal antibody to MUC5AC
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