Anti-HPC2 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
---|---|
Primary Accession | Q9BQ52 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 92219 Da |
Gene ID | 60528 |
---|---|
Other Names | HPC2; Zinc phosphodiesterase ELAC protein 2; ElaC homolog protein 2; Heredity prostate cancer protein 2; Ribonuclease Z 2; RNase Z 2; tRNA 3 endonuclease 2; tRNase Z 2 |
Target/Specificity | Recognizes endogenous levels of HPC2 protein. |
Dilution | WB~~1/500 - 1/1000 |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | ELAC2 |
---|---|
Synonyms | HPC2 |
Function | Zinc phosphodiesterase, which displays mitochondrial tRNA 3'- processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (PubMed:21593607). Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly (PubMed:24703694). |
Cellular Location | Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid. Nucleus Note=Mainly mitochondrial |
Tissue Location | Widely expressed. Highly expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, testis and ovary Weakly expressed in brain, lung, spleen, thymus, prostate, small intestine, colon and leukocytes. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Rabbit polyclonal antibody to HPC2
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