Anti-BLCAP Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IF |
---|---|
Primary Accession | P62952 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 9876 Da |
Gene ID | 10904 |
---|---|
Other Names | BC10; Bladder cancer-associated protein; Bladder cancer 10 kDa protein; Bc10 |
Target/Specificity | Recognizes endogenous levels of BLCAP protein. |
Dilution | WB~~1/500 - 1/1000 IF~~1/50 - 1/200 |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | BLCAP |
---|---|
Synonyms | BC10 |
Function | Acts as a tumor suppressor; induces growth arrest at G(1)/S checkpoint and apoptosis via RB1-dependent and p53/TP53- and NF-kappa- B-independent mechanisms (PubMed:16675915, PubMed:17031575, PubMed:21844121, PubMed:26986503). Modulates expression of genes involved in the regulation of proliferation, cell cycle and apoptosis (PubMed:17031575, PubMed:21844121, PubMed:26986503). |
Cellular Location | Cytoplasm. Nucleus. Membrane; Multi-pass membrane protein |
Tissue Location | Cervical tissues (at protein level) (PubMed:22969892). Urothelium (at protein level) (PubMed:19783793, PubMed:29190807). Endothelial cells of urinary bladder vessels (at protein level) (PubMed:19783793). Urinary bladder stromal cells (at protein level) (PubMed:19783793). Cervical tissues (PubMed:16675915) Kidney (PubMed:11072240). Ubiquitous (PubMed:19908260) |
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Provided below are standard protocols that you may find useful for product applications.
Background
Rabbit polyclonal antibody to BLCAP
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