Anti-A-MYB Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | P10243 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 85887 Da |
Gene ID | 4603 |
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Other Names | AMYB; Myb-related protein A; A-Myb; Myb-like protein 1 |
Target/Specificity | Recognizes endogenous levels of A-MYB protein. |
Dilution | WB~~1/500 - 1/1000 |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | MYBL1 |
---|---|
Synonyms | AMYB |
Function | Transcription factor that specifically recognizes the sequence 5'-YAAC[GT]G-3' (PubMed:7987850, PubMed:8058310). Acts as a master regulator of male meiosis by promoting expression of piRNAs: activates expression of both piRNA precursor RNAs and expression of protein-coding genes involved in piRNA metabolism (By similarity). The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity (By similarity). Transcriptional activator of SOX30 (By similarity). |
Cellular Location | Nucleus {ECO:0000250|UniProtKB:P51960}. |
Tissue Location | Expressed in a variety of lymphoid and solid tumor lines cultured in vitro |
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Provided below are standard protocols that you may find useful for product applications.
Background
Rabbit polyclonal antibody to A-MYB
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