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ATP6V1E1 Rabbit pAb
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB, IHC, FC, IP |
|---|---|
| Primary Accession | P36543 |
| Reactivity | Rat |
| Host | Rabbit |
| Clonality | Polyclonal Antibody |
| Calculated MW | 26145 Da |
| Gene ID | 529 |
|---|---|
| Other Names | V-type proton ATPase subunit E 1, V-ATPase subunit E 1, V-ATPase 31 kDa subunit, p31, Vacuolar proton pump subunit E 1, ATP6V1E1, ATP6E, ATP6E2 |
| Dilution | WB~~1:1000 |
| Name | ATP6V1E1 |
|---|---|
| Synonyms | ATP6E, ATP6E2 |
| Function | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:32001091, PubMed:33065002). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (PubMed:32001091). |
| Cellular Location | Apical cell membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:Q6PCU2}; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000250|UniProtKB:Q6PCU2}; Peripheral membrane protein |
| Tissue Location | Kidney; localizes to early distal nephron, encompassing thick ascending limbs and distal convoluted tubules (at protein level) (PubMed:29993276). Ubiquitous (PubMed:12036578). High expression in the skin (PubMed:28065471). |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Swiss-Prot Acc.P36543.
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$ 385.00
Cat# AP53527
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