DPF2 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q92785 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 44 KDa |
Antigen Region | 153-202 aa |
Gene ID | 5977 |
---|---|
Dilution | WB~~ 1:1000 |
Format | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | DPF2 |
---|---|
Synonyms | BAF45D, REQ, UBID4 |
Function | Plays an active role in transcriptional regulation by binding modified histones H3 and H4 (PubMed:27775714, PubMed:28533407). Is a negative regulator of myeloid differentiation of hematopoietic progenitor cells (PubMed:28533407). Might also have a role in the development and maturation of lymphoid cells (By similarity). Involved in the regulation of non-canonical NF-kappa-B pathway (PubMed:20460684). |
Cellular Location | Nucleus. Cytoplasm |
Tissue Location | Ubiquitous. |
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Provided below are standard protocols that you may find useful for product applications.
Background
May be a transcription factor required for the apoptosis response following survival factor withdrawal from myeloid cells. Might also have a role in the development and maturation of lymphoid cells.
References
Guru S.C.,et al.Genome Res. 7:725-735(1997).
Gabig T.G.,et al.Mamm. Genome 9:660-665(1998).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Taylor T.D.,et al.Nature 440:497-500(2006).
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