CNTROB Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q8N137 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 101 KDa |
Antigen Region | 589-638 aa |
Gene ID | 116840 |
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Dilution | WB~~ 1:1000 |
Format | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | CNTROB |
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Synonyms | LIP8 |
Function | Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis. |
Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Note=Centriole-associated, asymmetrically localizes to the daughter centriole |
Tissue Location | Widely expressed (at protein level). Highly expressed in testis. Also expressed in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes |
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Provided below are standard protocols that you may find useful for product applications.
Background
Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis.
References
Zou C.,et al.J. Cell Biol. 171:437-445(2005).
Wan D.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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