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Musashi-1 Antibody
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | O43347 |
| Reactivity | Human, Mouse |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Calculated MW | 39 KDa |
| Gene ID | 4440 |
|---|---|
| Other Names | MSI1;Musashi-1;Msi 1;Msi1;MSI1H_HUMAN;Musashi homolog 1;Musashi-1;Musashi1;RNA binding protein Musashi homolog 1;RNA-binding protein Musashi homolog 1. |
| Dilution | WB~~1:1000 |
| Format | Purified mouse monoclonal in PBS(pH 7.4) containing with 0.09% (W/V) sodium azide, 50% glycerol, 0.1%BSA |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | MSI1 |
|---|---|
| Function | RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU- 3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity). |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q61474}. Nucleus {ECO:0000250|UniProtKB:Q61474} |
| Tissue Location | Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
References
Good P.,et al.Genomics 52:382-384(1998).
Scherer S.E.,et al.Nature 440:346-351(2006).
Shu H.-J.,et al.Biochem. Biophys. Res. Commun. 293:150-154(2002).
Okano H.,et al.J. Cell Sci. 115:1355-1359(2002).
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).
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