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RAB4A Antibody
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P20338 |
| Reactivity | Human, Mouse |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Calculated MW | 24 KDa |
| Gene ID | 5867 |
|---|---|
| Other Names | HRES 1 / RAB4;Oncogene RAB4;OTTHUMP00000042824;Rab 4;RAB 4A;RAB4 member RAS oncogene family;RAB4A;RAB4A member RAS oncogene family;RAB4A_HUMAN;Ras related protein Rab 4A;Ras related protein Rab4A;Ras-related protein Rab-4A. |
| Dilution | WB~~1:500 |
| Format | Purified mouse monoclonal in PBS(pH 7.4) containing with 0.09% (W/V) sodium azide and 50% glycerol. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | RAB4A |
|---|---|
| Synonyms | RAB4 |
| Function | Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state (PubMed:15907487, PubMed:16034420). Involved in protein transport (PubMed:29425100). Plays a role in vesicular traffic. Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling (PubMed:29425100). Acts as a regulator of platelet alpha- granule release during activation and aggregation of platelets (By similarity). |
| Cellular Location | Membrane; Peripheral membrane protein. Cytoplasm Early endosome membrane {ECO:0000250|UniProtKB:P05714}; Peripheral membrane protein {ECO:0000250|UniProtKB:P05714}. Recycling endosome membrane {ECO:0000250|UniProtKB:P05714}; Peripheral membrane protein {ECO:0000250|UniProtKB:P05714}. Note=Generally associated with membranes. Cytoplasmic when phosphorylated by CDK1 |
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Provided below are standard protocols that you may find useful for product applications.
Background
Protein transport. Probably involved in vesicular traffic (By similarity).
References
Zahraoui A.,et al.J. Biol. Chem. 264:12394-12401(1989).
Nagy G.,et al.J. Biol. Chem. 281:34574-34591(2006).
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
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