SCRN1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, IHC-P, E |
---|---|
Primary Accession | Q12765 |
Other Accession | Q6AY84, Q9CZC8, P83939 |
Reactivity | Human |
Predicted | Bovine, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 46382 Da |
Antigen Region | 10-37 aa |
Gene ID | 9805 |
---|---|
Other Names | Secernin-1, SCRN1, KIAA0193 |
Target/Specificity | This SCRN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-37 amino acids from the N-terminal region of human SCRN1. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SCRN1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SCRN1 |
---|---|
Synonyms | KIAA0193 |
Function | Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity). |
Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene likely encodes a member of the secernin family of proteins. A similar protein in rat functions in regulation of exocytosis in mast cells. Alternatively spliced transcript variants have been described.
References
Suda, T., et al. Cancer Sci. 97(5):411-419(2006)
Way, G., et al. Mol. Biol. Cell 13(9):3344-3354(2002)
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