FGF19 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | O95750 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 24 KDa |
Gene ID | 9965 |
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Other Names | Fibroblast growth factor 19, FGF-19, FGF19 |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | FGF19 |
---|---|
Function | Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. |
Cellular Location | Secreted. |
Tissue Location | Expressed in fetal brain, cartilage, retina, and adult gall bladder. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.
References
Nishimura T.,et al.Biochim. Biophys. Acta 1444:148-151(1999).
Xie M.-H.,et al.Cytokine 11:729-735(1999).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).
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