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NICE4 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, ICC, E |
|---|---|
| Primary Accession | Q14157 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 115 KDa |
| Gene ID | 9898 |
|---|---|
| Other Names | Ubiquitin-associated protein 2-like, Protein NICE-4, UBAP2L, KIAA0144, NICE4 |
| Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | UBAP2L (HGNC:29877) |
|---|---|
| Synonyms | KIAA0144, NICE4 |
| Function | Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled nucleotide excision repair (TC-NER) machinery fails to resolve DNA damage (PubMed:35633597). Plays an important role in the activity of long-term repopulating hematopoietic stem cells (LT- HSCs) (By similarity). Is a regulator of stress granule assembly, required for their efficient formation (PubMed:29395067, PubMed:35977029). Required for proper brain development and neocortex lamination (By similarity). |
| Cellular Location | Nucleus. Chromosome. Cytoplasm Cytoplasm, Stress granule Note=Associates with nuclear chromatin. |
| Tissue Location | Ubiquitous.. |
Research Areas
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$ 385.00
Cat# AP51877
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