CD248 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9HCU0 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 80 KDa |
Gene ID | 57124 |
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Other Names | Endosialin, Tumor endothelial marker 1, CD248, CD248, CD164L1, TEM1 |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | CD248 |
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Synonyms | CD164L1, TEM1 |
Function | May play a role in tumor angiogenesis. |
Cellular Location | Membrane; Single-pass type I membrane protein |
Tissue Location | Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts. |
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Provided below are standard protocols that you may find useful for product applications.
Background
May play a role in tumor angiogenesis.
References
St Croix B.,et al.Science 289:1197-1202(2000).
Christian S.,et al.J. Biol. Chem. 276:7408-7414(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Rettig W.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:10832-10836(1992).
Dolznig H.,et al.Cancer Immun. 5:10-10(2005).
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