hnRNP E1 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q15365 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 37 KDa |
Antigen Region | 21 - 80 aa |
Gene ID | 5093 |
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Other Names | Poly(rC)-binding protein 1, Alpha-CP1, Heterogeneous nuclear ribonucleoprotein E1, hnRNP E1, Nucleic acid-binding protein SUB23, PCBP1 |
Target/Specificity | KLH conjugated synthetic peptide derived from human hnRNP E1 |
Dilution | WB~~ 1:1000 |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | PCBP1 {ECO:0000303|PubMed:7607214, ECO:0000312|HGNC:HGNC:8647} |
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Function | Single-stranded nucleic acid binding protein that binds preferentially to oligo dC (PubMed:15731341, PubMed:7556077, PubMed:7607214, PubMed:8152927). Together with PCBP2, required for erythropoiesis, possibly by regulating mRNA splicing (By similarity). |
Cellular Location | Nucleus. Cytoplasm. Note=Loosely bound in the nucleus (PubMed:7607214). May shuttle between the nucleus and the cytoplasm (PubMed:7607214). |
Tissue Location | Abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in prostate, spleen, testis, ovary, small intestine, heart, liver, adrenal and thyroid glands. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Single-stranded nucleic acid binding protein that binds preferentially to oligo dC.
References
Leffers H.,et al.Eur. J. Biochem. 230:447-453(1995).
Kiledjian M.,et al.EMBO J. 14:4357-4364(1995).
Aasheim H.-C.,et al.Nucleic Acids Res. 22:959-964(1994).
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
Olsen J.V.,et al.Cell 127:635-648(2006).
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