NPY2R Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, ICC, E |
---|---|
Primary Accession | P49146 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 43 KDa |
Gene ID | 4887 |
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Other Names | Neuropeptide Y receptor type 2, NPY2-R, NPY-Y2 receptor, Y2 receptor, NPY2R |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | NPY2R |
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Function | Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid. |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra |
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu- 31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
References
Gerald C.,et al.J. Biol. Chem. 270:26758-26761(1995).
Gehlert D.R.,et al.Mol. Pharmacol. 49:224-228(1996).
Rose P.M.,et al.J. Biol. Chem. 270:22661-22664(1995).
Yan H.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:4661-4665(1996).
Ammar D.A.,et al.Genomics 38:392-398(1996).
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