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NPY2R Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, ICC, E
Primary Accession P49146
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 43 KDa
Additional Information
Gene ID 4887
Other Names Neuropeptide Y receptor type 2, NPY2-R, NPY-Y2 receptor, Y2 receptor, NPY2R
Format 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name NPY2R
Function Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra
Research Areas
Citations (0)
citation

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Background

Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu- 31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.

References

Gerald C.,et al.J. Biol. Chem. 270:26758-26761(1995).
Gehlert D.R.,et al.Mol. Pharmacol. 49:224-228(1996).
Rose P.M.,et al.J. Biol. Chem. 270:22661-22664(1995).
Yan H.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:4661-4665(1996).
Ammar D.A.,et al.Genomics 38:392-398(1996).

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$ 350.00
Cat# AP51397
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