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FKBPL Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - FKBPL Antibody (C-term) AP5138b
    Western blot analysis of FKBPL Antibody (C-term) (Cat. #AP5138b) in HL-60 cell line lysates (35ug/lane).FKBPL (arrow) was detected using the purified Pab.
    detail
  • IHC-P - FKBPL Antibody (C-term) AP5138b
    FKBPL Antibody (C-term) (Cat. #AP5138b) IHC analysis in formalin fixed and paraffin embedded lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FKBPL Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
  • FC - FKBPL Antibody (C-term) AP5138b
    FKBPL Antibody (C-term) (Cat. #AP5138b) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
FC, IHC-P, WB, E
Primary Accession Q9UIM3
Other Accession Q6MG81, O35450
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 38176 Da
Antigen Region 264-292 aa
Additional Information
Gene ID 63943
Other Names FK506-binding protein-like, WAF-1/CIP1 stabilizing protein 39, WISp39, FKBPL, DIR1, NG7
Target/Specificity This FKBPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-292 amino acids from the C-terminal region of human FKBPL.
Dilution WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFKBPL Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FKBPL
Synonyms DIR1, NG7
Function May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.
Tissue Location Ubiquitously expressed with higher levels in testis.
Research Areas
Citations (0)
citation

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Background

FKBPL has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle.

References

McKeen, H.D., et al. Cancer Res. 70(3):1090-1100(2010)
Sunnotel, O., et al. Reprod. Biol. Endocrinol. 8, 22 (2010)
Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009)

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$ 182.50
$ 70.00
Cat# AP5138b
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