NF1 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, ICC, IHC-P, E |
---|---|
Primary Accession | P21359 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 250 KDa |
Gene ID | 4763 |
---|---|
Other Names | Neurofibromin, Neurofibromatosis-related protein NF-1, Neurofibromin truncated, NF1 |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | NF1 |
---|---|
Function | Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity. |
Cellular Location | Nucleus. Nucleus, nucleolus. Cell membrane |
Tissue Location | Detected in brain, peripheral nerve, lung, colon and muscle. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity.
References
Bernards A.,et al.DNA Cell Biol. 11:727-734(1992).
Wallace M.R.,et al.Science 249:181-186(1990).
Wallace M.R.,et al.Science 250:1749-1749(1990).
Marchuk D.A.,et al.Genomics 11:931-940(1991).
Suzuki H.,et al.Biochem. Biophys. Res. Commun. 187:984-990(1992).
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