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MT-ND1 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P03886 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 36 KDa |
| Gene ID | 4535 |
|---|---|
| Other Names | NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1, MT-ND1, MTND1, NADH1, ND1 |
| Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | MT-ND1 |
|---|---|
| Synonyms | MTND1, NADH1, ND1 |
| Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:1959619). Essential for the catalytic activity and assembly of complex I (PubMed:1959619, PubMed:26929434). |
| Cellular Location | Mitochondrion inner membrane {ECO:0000250|UniProtKB:P03887}; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
References
Anderson S.,et al.Nature 290:457-465(1981).
Horai S.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:532-536(1995).
Moilanen J.S.,et al.Mol. Biol. Evol. 20:2132-2142(2003).
Ingman M.,et al.Nature 408:708-713(2000).
Ingman M.,et al.Genome Res. 13:1600-1606(2003).
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