CD206 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IP, E |
---|---|
Primary Accession | P22897 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 166 KDa |
Gene ID | 4360 |
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Other Names | Macrophage mannose receptor 1, MMR, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, Macrophage mannose receptor 1-like protein 1, CD206, MRC1, CLEC13D, CLEC13DL, MRC1L1 |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | MRC1 |
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Synonyms | CLEC13D, CLEC13DL, MRC1L1 |
Function | Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. (Microbial infection) Acts as a receptor for Dengue virus envelope protein E. |
Cellular Location | Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.
References
Taylor M.E.,et al.J. Biol. Chem. 265:12156-12162(1990).
Ezekowitz R.A.,et al.J. Exp. Med. 172:1785-1794(1990).
Kim S.J.,et al.Genomics 14:721-727(1992).
Deloukas P.,et al.Nature 429:375-381(2004).
Taylor M.E.,et al.J. Biol. Chem. 267:1719-1726(1992).
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