Follistatin Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IP, IHC-P, E |
---|---|
Primary Accession | P19883 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 70 KDa |
Gene ID | 10468 |
---|---|
Other Names | Follistatin, FS, Activin-binding protein, FST |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | FST (HGNC:3971) |
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Function | Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). |
Cellular Location | Secreted. |
Tissue Location | Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid. In the embryo, strong expression is seen in the palatal epithelia, including the medial edge epithelial and midline epithelial seam of the palatal shelves. Less pronounced expression is also seen throughout the palatal shelf and tongue mesenchyme (PubMed:31215115). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).
References
Shimasaki S.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:4218-4222(1988).
Goshima N.,et al.Nat. Methods 5:1011-1017(2008).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).
Schneyer A.L.,et al.J. Clin. Endocrinol. Metab. 89:5067-5075(2004).
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