ELF5 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IP, ICC, E |
---|---|
Primary Accession | Q9UKW6 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 31 KDa |
Gene ID | 2001 |
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Other Names | ETS-related transcription factor Elf-5, E74-like factor 5, Epithelium-restricted ESE-1-related Ets factor, Epithelium-specific Ets transcription factor 2, ESE-2, ELF5, ESE2 |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | ELF5 |
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Synonyms | ESE2 |
Function | Transcriptionally activator that may play a role in regulating the later stages of keratinocytes terminal differentiation. |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00237}. |
Tissue Location | Expressed exclusively in tissues with a high content of epithelial cells. Highly expressed in salivary gland, mammary gland, kidney and prostate. Weakly expressed in placenta and lung. Isoform 1 and isoform 2 are differentially expressed in different tissues. In the kidney, only isoform 1 was expressed, while prostate expressed both isoforms, with levels of isoform 2 being higher Expression is up-regulated during keratinocyte differentiation. Several epithelial carcinoma cell lines showed lack of expression |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcriptionally activator that may play a role in regulating the later stages of keratinocytes terminal differentiation.
References
Zhou J.,et al.Oncogene 17:2719-2732(1998).
Oettgen P.,et al.J. Biol. Chem. 274:29439-29452(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Taylor T.D.,et al.Nature 440:497-500(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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