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BTG1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P62324 |
| Other Accession | P27049, Q04211, P78543, Q63073, P62325, P34743, P53348 |
| Reactivity | Human, Mouse |
| Predicted | Bovine, Chicken, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 19209 Da |
| Antigen Region | 92-118 aa |
| Gene ID | 694 |
|---|---|
| Other Names | Protein BTG1, B-cell translocation gene 1 protein, BTG1 |
| Target/Specificity | This BTG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-118 amino acids from the Central region of human BTG1. |
| Dilution | WB~~1:2000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | BTG1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BTG1 |
|---|---|
| Function | Anti-proliferative protein. |
Provided below are standard protocols that you may find useful for product applications.
Background
BTG1 is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia.
References
Camina-Tato, M., et al. J. Neuroimmunol. 213 (1-2), 142-147 (2009) Zemunik, T., et al. Croat. Med. J. 50(1):23-33(2009) Takahashi, N., et al. Exp. Hematol. 36(12):1760-1770(2008)
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