APLP2 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
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Primary Accession | Q06481 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 87 KDa |
Gene ID | 334 |
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Other Names | Amyloid-like protein 2, APLP-2, APPH, Amyloid protein homolog, CDEI box-binding protein, CDEBP, APLP2, APPL2 |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | APLP2 (HGNC:598) |
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Function | May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity). |
Cellular Location | Cell membrane; Single-pass type I membrane protein. Nucleus |
Tissue Location | Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues |
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Provided below are standard protocols that you may find useful for product applications.
Background
May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity).
References
Sprecher C.A.,et al.Biochemistry 32:4481-4486(1993).
Wasco W.,et al.Nat. Genet. 5:95-99(1993).
von der Kammer H.,et al.DNA Cell Biol. 13:1137-1143(1994).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Vostrov A.A.,et al.Submitted (AUG-1993) to the EMBL/GenBank/DDBJ databases.
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