Acetylcholinesterase Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P22303 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 70 KDa |
Gene ID | 43 |
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Other Names | Acetylcholinesterase, AChE, ACHE |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | ACHE (HGNC:108) |
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Function | Hydrolyzes rapidly the acetylcholine neurotransmitter released into the synaptic cleft allowing to terminate the signal transduction at the neuromuscular junction. Role in neuronal apoptosis. |
Cellular Location | Synapse. Secreted. Cell membrane; Peripheral membrane protein [Isoform H]: Cell membrane; Lipid- anchor, GPI-anchor; Extracellular side |
Tissue Location | Isoform H is highly expressed in erythrocytes. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.
References
Soreq H.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:9688-9692(1990).
Karpel R.,et al.Exp. Cell Res. 210:268-277(1994).
Yang L.,et al.Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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