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Mnk1 Antibody (Ab-385)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9BUB5 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 51,47,39 KDa |
| Antigen Region | 365-395 aa |
| Gene ID | 8569 |
|---|---|
| Other Names | MAP kinase-interacting serine/threonine-protein kinase 1, MAP kinase signal-integrating kinase 1, MAPK signal-integrating kinase 1, Mnk1, MKNK1, MNK1 |
| Dilution | WB~~ 1:250-1:1000 |
| Format | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol. |
| Storage Conditions | -20℃ |
| Name | MKNK1 |
|---|---|
| Synonyms | MNK1 |
| Function | May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine- containing mRNA cap. |
| Cellular Location | [Isoform 2]: Cytoplasm. |
| Tissue Location | Ubiquitous.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap.
References
Fukunaga R.,et al.EMBO J. 16:1921-1933(1997).
Knauf U.,et al.Mol. Cell. Biol. 21:5500-5511(2001).
O'Loghlen A.,et al.Exp. Cell Res. 299:343-355(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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