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FCGR1A Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | P12314 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 42632 Da |
| Antigen Region | 217-245 aa |
| Gene ID | 2209 |
|---|---|
| Other Names | High affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I, Fc-gamma RI, FcRI, Fc-gamma RIA, FcgammaRIa, CD64, FCGR1A, FCG1, FCGR1, IGFR1 |
| Target/Specificity | This FCGR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-245 amino acids from the Central region of human FCGR1A. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FCGR1A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FCGR1A |
|---|---|
| Synonyms | FCG1, FCGR1, IGFR1 |
| Function | High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein Note=Stabilized at the cell membrane through interaction with FCER1G |
| Tissue Location | Monocyte/macrophage specific. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
FCGR1A encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.
References
Poon, I.K., et al. Blood 115(12):2473-2482(2010)
Jung, S.T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(2):604-609(2010)
Hulse, K.E., et al. J. Allergy Clin. Immunol. 125(1):247-256(2010)
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