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PAH Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P00439 |
| Other Accession | P04176, P16331, Q2KIH7 |
| Reactivity | Human, Mouse |
| Predicted | Bovine, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 51862 Da |
| Antigen Region | 132-161 aa |
| Gene ID | 5053 |
|---|---|
| Other Names | Phenylalanine-4-hydroxylase, PAH, Phe-4-monooxygenase, PAH |
| Target/Specificity | This PAH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-161 amino acids from the Central region of human PAH. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PAH Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PAH |
|---|---|
| Function | Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
PAH encodes the enzyme phenylalanine hydroxylase that is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria.
References
Bonyadi, M., et al. Genet Test Mol Biomarkers 14(2):233-235(2010)
Dupuis, J., et al. Nat. Genet. 42(2):105-116(2010)
Santos, L.L., et al. Genet. Mol. Res. 9(1):1-8(2010)
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