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PSMD7 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - PSMD7 Antibody (N-term) AP2916a
    Western blot analysis of PSMD7 Antibody (N-term) (Cat. #AP2916a) in A375 cell line lysates (35ug/lane). PSMD7 (arrow) was detected using the purified Pab.
    detail
  • IHC-P - PSMD7 Antibody (N-term) AP2916a
    Formalin-fixed and paraffin-embedded human skin tissue reacted with PSMD7 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
    detail
  • FC - PSMD7 Antibody (N-term) AP2916a
    PSMD7 Antibody (N-term) (Cat. #AP2916a) flow cytometric analysis of CEM cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
FC, IHC-P, WB, E
Primary Accession P51665
Other Accession P26516, Q3ZBD0
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 37025 Da
Antigen Region 6-34 aa
Additional Information
Gene ID 5713
Other Names 26S proteasome non-ATPase regulatory subunit 7, 26S proteasome regulatory subunit RPN8, 26S proteasome regulatory subunit S12, Mov34 protein homolog, Proteasome subunit p40, PSMD7, MOV34L
Target/Specificity This PSMD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human PSMD7.
Dilution WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPSMD7 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PSMD7
Synonyms MOV34L
Function Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Research Areas
Citations (0)
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Background

PSMD7 acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.

References

Dastani,Z., et.al., Eur. J. Hum. Genet. (2009) In press
Sanches,M., et.al., J. Mol. Biol. 370 (5), 846-855 (2007)

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$ 182.50
$ 70.00
Cat# AP2916a
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