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FABP4 Antibody (Y20)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - FABP4 Antibody (Y20) AP2764d
    All lanes : Anti-FABP4 Antibody (Y20) at 1:2000-1:8000 dilution Lane 1: Human skeletal muslce lysate Lane 2: Human lung lysate Lane 3: Human heart lysate Lane 4: Rat heart lysate Lane 5: 3T3/L1 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 15 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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  • SPECIFICATION
  • CITATIONS: 1
  • PROTOCOLS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P15090
Other Accession P70623, O97788, P04117, P48035
Reactivity Human, Mouse, Rat
Predicted Bovine, Pig
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 14719 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 2167
Other Names Fatty acid-binding protein, adipocyte, Adipocyte lipid-binding protein, ALBP, Adipocyte-type fatty acid-binding protein, A-FABP, AFABP, Fatty acid-binding protein 4, FABP4
Target/Specificity This FABP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human FABP4.
Dilution WB~~1:2000-1:8000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFABP4 Antibody (Y20) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FABP4
Function Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:P04117}. Nucleus {ECO:0000250|UniProtKB:P04117}. Note=Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export. {ECO:0000250|UniProtKB:P04117}
Research Areas
Citations ( 0 )

Background

FABP4 is a fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism.

References

Cabre,A., J. Lipid Res. 49 (8), 1746-1751 (2008)
Fasshauer,M., Am. J. Hypertens. 21 (5), 582-586 (2008)
Cabre,A., Clin. Chem. 54 (1), 181-187 (2008)

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$ 182.50
$ 70.00
Cat# AP2764d
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