Pax-8
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q06710 |
Reactivity | Human |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit Ig |
Calculated MW | 48218 Da |
Gene ID | 7849 |
---|---|
Other Names | Paired box protein Pax-8, PAX8 |
Target/Specificity | This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Pax-8 is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PAX8 |
---|---|
Function | Transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, maintaining the functional differentiation of such cells. |
Cellular Location | Nucleus. |
Tissue Location | Expressed in the excretory system, thyroid gland and Wilms tumors |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, maintaining the functional differentiation of such cells.
References
Poleev A.,et al.Development 116:611-623(1992).
Kozmik Z.,et al.Mol. Cell. Biol. 13:6024-6035(1993).
Poleev A.,et al.Eur. J. Biochem. 228:899-911(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
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