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COL14A1 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, IHC-P, E |
|---|---|
| Primary Accession | Q05707 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 193515 Da |
| Gene ID | 7373 |
|---|---|
| Other Names | Collagen alpha-1(XIV) chain, Undulin, COL14A1 (HGNC:2191), UND |
| Target/Specificity | This COL14A1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 643-677 amino acids from the Central region of human COL14A1. |
| Dilution | WB~~1:2000 IHC-P~~1:25 FC~~1:25 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | COL14A1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | COL14A1 (HGNC:2191) |
|---|---|
| Synonyms | UND |
| Function | Plays an adhesive role by integrating collagen bundles. It is probably associated with the surface of interstitial collagen fibrils via COL1. The COL2 domain may then serve as a rigid arm which sticks out from the fibril and protrudes the large N-terminal globular domain into the extracellular space, where it might interact with other matrix molecules or cell surface receptors (By similarity). |
| Cellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P32018} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Plays an adhesive role by integrating collagen bundles. It is probably associated with the surface of interstitial collagen fibrils via COL1. The COL2 domain may then serve as a rigid arm which sticks out from the fibril and protrudes the large N-terminal globular domain into the extracellular space, where it might interact with other matrix molecules or cell surface receptors (By similarity).
References
Nusbaum C.,et al.Nature 439:331-335(2006).
Bauer M.,et al.Biochim. Biophys. Acta 1354:183-188(1997).
Just M.,et al.J. Biol. Chem. 266:17326-17332(1991).
Brown J.C.,et al.Matrix Biol. 14:287-295(1994).
Schuppan D.,et al.J. Biol. Chem. 265:8823-8832(1990).
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